Zoom out from CU of morphine bottle. Zoom in on amphetamine pills spelling out the number "20." Narrator explains that tolerance leads users to take higher doses to achieve same effects. Zoom out on three nearly empty liquor bottles. CU red capsules and white pills, intercut with shots of concertgoers at a music festival. Shots of drinks behind a bar, bar patron, pills, drunk people sitting on stairs at music festival. Nine illuminated disks representing nine systems of the body begin to flash in front of three pedestals representing the depressant classes of drugs as narrator explains the concept of withdrawals.